Trivia: The bar "Mahoney's" is named after the late John Mahoney, who played Frasier's father in the original show.
Trivia: The name on Jenkins' disguise is "Chuck Spadina." When Keanu Reeves first came to Hollywood, he was told his name was "a little too exotic," and it was suggested he should change his name. Chuck Spadina was one option he considered, although apparently not very seriously.
Trivia: Willa is played by Timothy Olyphant's daughter Vivian.
Trivia: Several actors from the original series are returning to voice different characters. Chris Potter, who voiced Gambit, will now be voicing Cable, while original Cable actor, Lawrence Bayne, will be voicing X-Cutioner. Catherine Disher, who voiced Jean Grey, will be voicing Valerie Cooper. Ron Rubin, who voiced Morph, will be voicing President Kelly. Alyson Court, who voiced Jubilee, will be voicing Abcissa, who is an older and digital replica of Jubilee.
Trivia: Ashley Johnson plays Anna Williams, the mother of Ellie. Johnson voiced Ellie in the video game the show is based on.
Trivia: S01e9, "Bitter Sweethearts", features Tom Arnold playing Arnie Orwig. Tom Arnold starred in the "True Lies" film. The name Arnie could be a reference to his "True Lies" co-star Arnold Schwarzenegger (who is sometimes called Arnie") or his "Roseanne" character, Arnie Thomas.
Trivia: Charlie (Milo Ventimiglia) is asked to help break someone out of prison. He says he doesn't do prison breaks. Listening in on the bug Charlie is wearing is his sister Birdie, played by Sarah Wayne Callies. Callies starred in Fox's Prison Break.
Trivia: Lars Mikkelsen, who plays Grand Admiral Thrawn and voiced him in Star Wars: Rebels, is the older brother of Mads Mikkelsen, who played Galen Erso in Rogue One: A Star Wars Story.